An eight-game losing streak in Minnesota will be the stat the reverberates loudest from the San Francisco 49ers' 23-17 loss to the Vikings on Sunday. It isn't the stat that defines their defeat.

The 49ers had a slew of issues in their Week 2 defeat. Some of them may be chalked up to the quick turnaround from Monday night to an early West Coast kickoff Sunday. Others look like bigger problems that go beyond quirks of the schedule.

Here are five stats from Sunday that defined the 49ers' eighth-straight faceplant in Minnesota:

Purdy under pressure

There are a couple of reasons the pressure on Brock Purdy was a problem Sunday. ESPN's Nick Wagoner noted that Purdy was under pressure on a career-high 13 dropbacks, and a sacked a career-high six times. Part of it was just a matter of Vikings defensive coordinator Brian Flores blitzing a ton. However, Purdy and the 49ers didn't have any answers for the aggressive blitzing Vikings defense. Giving up that many pressures is a problem on its own.

The other issue was some general indecisiveness by Purdy. He looked hesitant and uncomfortable in the pocket in ways he hasn't really as a pro. Minnesota sped him up and his response in some spots was to hold onto the ball which probably led to more pressures than he should have taken. This is something the 49ers must iron out as soon as possible.

No leads since 2009

It isn't just that the 49ers lose in Minnesota. They haven't won there since 1992. Somehow, it got worse Sunday. The Vikings led wire-to-wire, marking the fourth consecutive game Minnesota has led the 49ers wire-to-wire at home. San Francisco couldn't make the Vikings uncomfortable after falling behind late, and they didn't look nearly as dominant playing from behind. If they're going to struggle in any game they fall behind in, it's going to be a major problem.

Third-down offense

Typically the 49ers are good on third downs. They were bad Sunday, and this is another spot McCaffrey's absence hurts. San Francisco was 2-for-10 on third downs, and both conversions went to tight end George Kittle. Extending drives and winning on third downs is essential, and the 49ers' overall bad offensive performance can be whittled down to failing to turn third downs into a new set of downs.

Third-down defense

San Francisco couldn't get off the field on third down all game. Minnesota finished 7-of-12 in those spots. It's especially bad in this situation because the Vikings had success without their top two WRs, Justin Jefferson and Jordan Addison, and their starting TE TJ Hockenson. The 49ers' putrid third-down defense reared its head on the Vikings' final scoring drive when they converted three-of-four, including a third-and-11 from their own 33, and then a third-and-8 from their own 46. The inability to get off the field on third down has been a problem for the 49ers in both of their games this season, and it was an issue again in Sunday's loss.

Longest TD pass ever

According to the AP's Josh Dubow, Sam Darnold's 97-yard touchdown pass to Justin Jefferson was the longest touchdown pass ever thrown against the 49ers. It broke a 74-year-old record of 96 yards, set by the Packers' Tobin Rote and Billy Grimes.

It was the turning point in the game because the 49ers, trailing 3-0, were denied on a fourth-and-goal from the 2. Two plays later Darnold aired it out to Jefferson, who got in behind both 49ers safeties for the long touchdown. The score flipped the field, flipped the game, and led to the benching of veteran safety George Odum. San Francisco never climbed out of the 10-0 hole.

This article originally appeared on Niners Wire: 5 bad 49ers stats that defined Week 2 loss at Minnesota