The inaugural MLB Spring Breakout Series is set for Thursday through Sunday at spring training stadiums in Arizona and Florida.

The series, which features 16 games, will include the top prospects from each team. Several players with Oklahoma ties are set to play in it, most notably Jackson Holliday and Cade Horton.

A Stillwater graduate, Holliday — a middle infielder in the Baltimore Orioles organization — is the top prospect in baseball and was the No. 1 pick in the 2022 MLB Draft.

He set a national record for hits in a season during his senior year at Stillwater with 89. The previous record was 88 and set in 2010 by Philadelphia Phillies catcher and former Carl Albert star JT Realmuto.

Horton, a former Norman and OU star, is the No. 26 prospect in baseball.

A right-handed pitcher, he was selected by the Chicago Cubs with the seventh pick in the 2022 draft shortly after helping the Sooners reach the Men’s College World Series championship during his redshirt freshman season.

Here is how to watch the MLB Spring Breakout Series and a list of players with Oklahoma ties who made rosters.

More: OSU baseball coach Josh Holliday says Bedlam vs. OU will continue 'for years to come'

How to watch the 2024 MLB Spring Breakout Series

• Thursday, 5:05 p.m.: Reds at Rangers (MLB.com)*

• Thursday, 6:05 p.m.: Orioles at Pirates (MLBN, ESPN+, ESPN.com)*

• Friday, 1:05 p.m.: Marlins at Cardinals (MLBN, ESPN+, MLB.com)*

• Friday, 2:20 p.m.: Nationals at Mets (ESPN+, MLB.com)*

• Friday, 3:10 p.m.: Padres at Mariners (MLBN, ESPN+, MLB.com, Padres.tv)

• Friday, 4:05 p.m.: White Sox at Cubs (ESPN+, MLB.com)

• Friday, 6:05 p.m.: Giants at Athletics (MLB.com)*

• Saturday, 12:05 p.m.: Braves at Red Sox (MLBN, ESPN+, MLB.com)

• Saturday, 12:05 p.m.: Phillies at Tigers (ESPN+, MLB.com, Tigers.tv)

• Saturday, 3:05 p.m.: Blue Jays at Yankees (MLBN, ESPN+, MLB.com)*

• Saturday, 3:05 p.m.: Rays at Twins (MLB.com)*

• Saturday, 6:10 p.m.: Dodgers at Angels (MLB.com)*

• Saturday, 6:10 p.m.: Guardians at Reds (MLB.com)*

• Saturday, 6:10 p.m.: Diamondbacks at Rockies (MLBN, ESPN+, MLB.com, Rockies.tv)

• Sunday, 9:05 a.m.: Astros at Cardinals (MLB.com)

• Sunday, 3:05 p.m.: Brewers at Royals (MLB.com)

*This will be a seven-inning matchup as it will be a part of a doubleheader with a spring training game. 

Former Oklahoma State players who made MLB Spring Breakout Series rosters

Angels: Bryce Osmond, P (Jenks HS)

Athletics: Brady Basso, P, and Caeden Trenkle, OF

Dodgers: Justin Wrobleski, P

Guardians: Justin Campbell, P

Mets: Nolan McLean, P/Utility

Rays: Trevor Martin, P (Asher HS)

Yankees: Roc Riggio, 2B

More: Oklahoma State baseball: Get to know the 2024 OSU Cowboys roster, schedule

Former OU players who made MLB Spring Breakout Series rosters

Cardinals: Jimmy Crooks III, C

Cubs: Cade Horton, P (Norman HS)

Rangers: Dane Acker, P

Red Sox: David Sandlin, P (Owasso HS, Eastern Oklahoma State)

Royals: Brett Squires, 1B

More: OU baseball: Get to know the 2024 Oklahoma Sooners roster, schedule

Former Oklahoma high school stars who made MLB Spring Breakout Series rosters

Blue Jays: Jace Bohrofen, OF (Westmoore, Arkansas/OU)

Braves: Cody Milligan, OF (Binger-Oney, Cowley College/OSU)

Cubs: Kohl Franklin, P (Broken Arrow)

Orioles: Jackson Holliday, SS/2B (Stillwater)

Why Jackson Jobe isn't playing at the MLB Spring Breakout Series

The former Heritage Hall star, who was drafted by the Detroit Tigers with the third pick in the 2021 draft, pitched Tuesday and therefore will not play at the MLB Spring Breakout Series.

Although he won't pitch in the series, Jobe's future looks bright.

More: Detroit Tigers prospect Jackson Jobe shows 'pretty special stuff' in Grapefruit League debut

He hit 102 mph in his spring debut, and there's a lot of optimism surrounding the 21-year-old right-hander.

This article originally appeared on Oklahoman: Jackson Holliday, Cade Horton to play at MLB Spring Breakout Series