The first rule of fantasy football after Week 1 is simple: Don't panic.

But that's far easier said than done. With all the injuries last week and the uncertainty over how the new season will play out, fantasy managers have some tough calls to make in Week 2. That's why we're here to help.

These fantasy football rankings are based on the point-per-reception (PPR) scoring used in most seasonal and daily fantasy football formats. One point is awarded for every 10 rushing and receiving yards and one point for every 20 passing yards. Six points are awarded for touchdowns scored, four points for passing TDs and one point for receptions.

Rankings are compiled by Daniel Dobish, TheHuddle.com. 

(*-check status before kickoff)

Fantasy football Week 2 quarterback rankings

• Justin Fields is expected to get another start for Pittsburgh with Russell Wilson still dealing with a calf injury.

• Jordan Love (knee) is inactive. Mailk Willis will start, which would result in a downgrade for Packers receivers.

• Josh Allen injured his left hand in Week 1 diving for a touchdown, but has been cleared to practice and should be fine to start on Thursday night.

Fantasy football Week 2 running back rankings

• Kenneth Walker (oblique) is inactive. Zach Charbonnet doesn't have Walker's upside, but will get the start and most of the work.

• Christian McCaffrey (calf, Achilles) has been put on injured reserve, meaning he will miss a minimum of four games. The Niners can feel more comfortable giving him extra time to recover after Jordan Mason's big game (152 rushing yards, TD) on Monday night. Mason makes a big move up in this week's rankings.

• De'Von Achane (ankle) is questionable and Raheem Mostert (chest) is out for Thursday night vs. Buffalo. Look for Jeff Wilson Jr. to see more reps with Jaylen Wright set to make his NFL debut due to the short week.

Fantasy football Week 2 wide receiver rankings

• UPDATE: A.J. Brown (hamstring) is officially out for Monday night. Could we have a Jahan Dotson sighting?

• The Bears' Keenan Allen (heel) is questionable after practicing on a limited basis Friday. He looks like he'll be a game-time decision on Sunday night. Teammate Rome Odunze (knee) is also questionable but appears to have a better chance of playing.

• Tee Higgins (hamstring) has yet to return to practice after sitting out Week 1. He is listed as doubtful.

• The Vikings' Jordan Addison has been ruled out for Sunday due to soreness in his right ankle.

Fantasy football Week 2 tight end rankings

• Evan Engram has surprisingly been ruled out after injuring his hamstring during pregame warmups.

• David Njoku (ankle) has been ruled out for Week 2. Jordan Akins is the next man up.

• Jake Ferguson is dealing with an MCL sprain and a bone bruise in his knee, but the Cowboys haven't officially ruled him out for Sunday.

Fantasy football Week 2 kicker rankings

• Graham Gano is dealing with a groin injury, but does not have an injury designation.

Fantasy football Week 2 defense/special teams rankings

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This article originally appeared on USA TODAY: Fantasy football Week 2: PPR rankings for every position