In Week 4, the Pittsburgh Steelers' impressive defensive line meets one of the best offensive lines in the NFL. No matchup is more important than the heart of the Steelers' defensive line—Cameron Heyward—facing one of the league's most violent guards, Colts' Quenton Nelson.

Nelson is one of the best pass-protecting guards in the league: zero sacks, zero quarterback hits, and zero pressures allowed through 87 passing plays in three games. The running lanes for star RB Jonathan Taylor are often created by four-time All-Pro Nelson’s elite run blocking.

Heyward is turning back the clock, still proving he has elite performances left in the tank at 35 years old. Through 66 passing plays, Heyward has recorded 2 sacks, 2 quarterback hits, and 10 pressures. His run defense has been outstanding, plugging up run lanes, absorbing double teams, and even securing 2 tackles for loss. Pittsburgh will need this matchup to swing in their favor, or they could fall victim to a potential trap game in Indianapolis.

The Steelers and Colts lock horns this Sunday, Sept. 29, at 1 p.m. EST, with the Steelers looking to improve their undefeated record to 4-0.

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This article originally appeared on Steelers Wire: Steelers-Colts matchups to watch: Cameron Heyward vs. Quenton Nelson