Green Bay Packers at San Francisco 49ers: Predictions, picks and odds for NFL divisional game
After pulling off the stunner of wild card weekend, the Green Bay Packers (10-8) face another NFC power when they visit the San Francisco 49ers (12-5) on Saturday with a spot in the conference championship on the line.
In a game where they entered as heavy underdogs, the Packers not only stunned the Dallas Cowboys but blew them out in convincing fashion to complete the upset and advance to the divisional round. It was the first time the seventh seed won a playoff game, and Green Bay isn't looking like a young, inexperienced team playing in the playoffs.
San Francisco got to enjoy the benefit of being the No. 1 seed in the NFC by having the first round off, which seemed much needed given the injuries to some of its stars. Facing a team coming off a major victory, can the 49ers assert themselves as a top Super Bowl contender, or will Green Bay pull off another incredible win in an NFL-record 10th all-time playoff meeting between the teams?
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49ers vs. Packers odds, moneyline, over/under
The 49ers are favorites to defeat the Packers, according to the BetMGM NFL odds. Looking to wager? Check out the best mobile sports betting apps offering NFL betting promos in 2023, including the new ESPN BET app and the Fanatics Sportsbook promo code.
Spread: 49ers (-10)
Moneyline: 49ers (-450); Packers (+350)
Over/under: 50.5
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NFL divisional round odds, predictions and picks
AFC: Ravens vs. Texans | Bills vs. Chiefs
NFC: 49ers vs. Packers | Lions vs. Buccaneers
Lorenzo Reyes: Packers 24, 49ers 22
This, admittedly, is a bit of a risk, but Green Bay’s offense is playing hyper-efficient ball with Jordan Love conducting the offense. The downfield passing game is thriving and San Francisco’s secondary is something of a weak spot. The Packers can also run the ball quite well, so with rain potentially in the forecast, I think Green Bay is playing hot enough for the upset here. That said, the Niners are very talented so as tempting as the Packers on the moneyline sounds, taking the points is the safer play.
Tyler Dragon: 49ers 28, Packers 17
The 49ers have an all-time 5-4 postseason record against the Packers. Expect San Francisco to increase it to six wins. Jordan Love and the Packers had an impressive win in Dallas last week, but the 49ers pose a different challenge. The 49ers have a formidable defense and an offense that imposes its will against opposing defenses. The 49ers averaged a league-high 6.6 per play in 2023. The defense held opponents to 44 red zone drives, the fewest in the NFC. The road to Las Vegas is going through San Francisco in the NFC.
Safid Deen: 49ers 27, Packers 23
Can the Packers force Brock Purdy to turn the ball over and Kyle Shanahan to abort his game plan? It’s likely, but a tall task. The 49ers have been to two straight NFC title games and won’t let the Packers ruin their chance to reach a third.
Victoria Hernandez: 49ers 28, Packers 21
A lot of this game will depend on how healthy the 49ers were able to get with the first-round bye. Brock Purdy had a stinger and Christian McCaffrey had an injured calf that he said he would have played through if he had to. San Francisco is the better team on paper and will probably continue their march to another NFC championship appearance. But that nearly 10-point spread doesn’t bode well against an energized Packers team that put up 48 points on the Cowboys' defense.
Jordan Mendoza: 49ers 27, Packers 23
The 49ers and Packers have given fans some classic playoff games − especially in recent memory − but the playoff series has recently been owned by San Francisco. Jordan Love was near-perfect against the Cowboys, but it's a tough ask to do the same against a top-tier defense in the 49ers. Green Bay keeps in closer than most think, but the 49ers prevail against a pesky team to advance. The spread seems wide, so there's no issue in picking the Packers to cover.
You can view the full list of USA TODAY's NFL expert predictions here.
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This article originally appeared on USA TODAY: Green Bay Packers at San Francisco 49ers: Playoff predictions, picks and odds
