INDIANAPOLIS -- The Colts' backfield could be down to primarily Jonathan Taylor again.

Zack Moss missed the full week of practice following the forearm injury he suffered on his touchdown catch against the Steelers on Saturday. He will be listed as questionable on the game status report, but it's rare for players to play after missing a full week of practice.

Taylor, meanwhile, had three full practices after missing the past three games after thumb surgery. His status will become more certain when the game status report is released Friday afternoon.

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But he won't have his right tackle to run behind. Braden Smith will miss his seventh game of the season, this time with a knee injury. Fourth-round BYU rookie Blake Freeland will start his ninth game this season.

The Colts have also ruled out center Jack Anderson (illness) and linebacker Segun Olubi (hip).

They could have Michael Pittman Jr. back after he entered the concussion protocol following a vicious hit from Damontae Kazee. Despite the hit knocking him to the ground for several minutes and leading to Kazee's ejection and eventual three-game suspension from the NFL, Pittman was able to clear the steps of the protocol in order to practice Thursday and Friday. He is questionable for the game from a shoulder injury, which he suffered on Saturday in addition to the brain injury.

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The Colts' hope is that Pittman and Taylor can ignite the offense the way they used to when both were healthy. Whereas Pittman is leading the team in receiving again, Taylor has managed to play just seven games this year and has yet to cross 100 yards in any of them. He is averaging 4.1 yards per carry, down from his career average of 5.0.

At 8-6, the Colts are looking to keep pace in a crowded AFC wildcard race, whereas the 6-8 Falcons still have a lane in the NFC South if they can pull out a win.

Contact Nate Atkins at natkins@indystar.com. Follow him on Twitter @NateAtkins_.

This article originally appeared on Indianapolis Star: Colts run game could take a hit with Zack Moss' injury